Collagen Induction Therapy, or CIT, utilizes microsurgical titanium steel needles to penetrate the skin creating micro openings in the top layer of the skin, thus stimulating the lower layers to produce more collagen and elastin without major damage or pain. Just as you have to stress muscle fibers to build more muscle, this stress on the lower layers of skin will stimulate the body to self-repair with more structural support!
The micro-trauma to the skin created by the needle tips activates blood to the treated site (erythema/redness & in some cases pinpoint bleeding) which releases natural growth factors and in return creates the cellular matrix. Synthesis of new collagen, elastin, Glycosaminoglycans & Mucopolysaccharides, CIT Microneedling, and Angiogenesis (forming of new blood vessels) will take place. Creating microscopic channels (artificial holes) in the skin triggers a repair system. Fibroblast cells work to replace collagen fibers of the skin and begin to repair. The cell renewal is stimulated and the skin starts making more collagen and elastin.
BONE MARROW-DERIVED STEM CELLS
AnteAGE by Cellese
Recent research revealed the important role The stem cells we use are derived from Bone marrow. marrow stem cells play in tissue repair and healing throughout the body, particularly in the skin. Like red cells, white cells, and platelets, which also originate in the bone marrow, these stem cells enter the bloodstream, carrying them to all tissues. Upon arrival at injuries, some may differentiate into cell types needed for repair (e.g. muscle, cartilage, nerve, etc.). Their major role, however, is to command and control other nearby cells involved in healing. The pattern of bio-signals in conditioned media derived from the culture of bone marrow stem cells is strongly anti-inflammatory. Based on healing physiology, and the known deleterious effects of inflammation on the skin, CIT Microneedling, bone marrow-derived mesenchymal stem cells appear to be the preferred cell to culture to obtain bio-signals for use in products to be applied to the skin. Clinical evidence supports this conclusion. Bone marrow stem cells are typically obtained from young adults in their early 20’s.
John Sanderson MD, George Taylor MD COPYRIGHT © 2014 CELLESE REGENERATIVE THERAPEUTICS
